Retrospective analysis of Vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa

The manual broth micro-dilution (mBMD) is the recommended reference method for colistin minimum inhibitory concentration determination; however, it is not as readily available in South Africa as the Vitek(®)2. This retrospective study compared the performance of Vitek(®)2 against mBMD in determining...

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Autores principales: Fadana, Vuyolwethu, Thomas, Teena, von Knorring, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905463/
https://www.ncbi.nlm.nih.gov/pubmed/35282395
http://dx.doi.org/10.4102/ajlm.v11i1.1597
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author Fadana, Vuyolwethu
Thomas, Teena
von Knorring, Nina
author_facet Fadana, Vuyolwethu
Thomas, Teena
von Knorring, Nina
author_sort Fadana, Vuyolwethu
collection PubMed
description The manual broth micro-dilution (mBMD) is the recommended reference method for colistin minimum inhibitory concentration determination; however, it is not as readily available in South Africa as the Vitek(®)2. This retrospective study compared the performance of Vitek(®)2 against mBMD in determining the colistin minimum inhibitory concentration of 337 extensively drug-resistant Acinetobacter baumannii complex isolates. Vitek(®)2 yielded a categorical agreement of 89%, an essential agreement of 56%, a major error rate of 8% and a very major error rate of 55%. The Vitek(®)2 is not an alternative to mBMD for colistin susceptibility testing.
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spelling pubmed-89054632022-03-10 Retrospective analysis of Vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa Fadana, Vuyolwethu Thomas, Teena von Knorring, Nina Afr J Lab Med Brief Report The manual broth micro-dilution (mBMD) is the recommended reference method for colistin minimum inhibitory concentration determination; however, it is not as readily available in South Africa as the Vitek(®)2. This retrospective study compared the performance of Vitek(®)2 against mBMD in determining the colistin minimum inhibitory concentration of 337 extensively drug-resistant Acinetobacter baumannii complex isolates. Vitek(®)2 yielded a categorical agreement of 89%, an essential agreement of 56%, a major error rate of 8% and a very major error rate of 55%. The Vitek(®)2 is not an alternative to mBMD for colistin susceptibility testing. AOSIS 2022-02-28 /pmc/articles/PMC8905463/ /pubmed/35282395 http://dx.doi.org/10.4102/ajlm.v11i1.1597 Text en © 2022. The Authors https://creativecommons.org/licenses/by/4.0/Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Brief Report
Fadana, Vuyolwethu
Thomas, Teena
von Knorring, Nina
Retrospective analysis of Vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa
title Retrospective analysis of Vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa
title_full Retrospective analysis of Vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa
title_fullStr Retrospective analysis of Vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa
title_full_unstemmed Retrospective analysis of Vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa
title_short Retrospective analysis of Vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa
title_sort retrospective analysis of vitek(®)2 performance compared to manual broth micro-dilution for colistin susceptibility testing of acinetobacter baumanniicomplex isolates in south africa
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905463/
https://www.ncbi.nlm.nih.gov/pubmed/35282395
http://dx.doi.org/10.4102/ajlm.v11i1.1597
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