Optimizing CSP1 analogs for modulating quorum sensing in Streptococcus pneumoniae with bulky, hydrophobic nonproteogenic amino acid substitutions

The prompt appearance of multiantibiotic-resistant bacteria necessitates finding alternative treatments that can attenuate bacterial infections while minimizing the rate of antibiotic resistance development. Streptococcus pneumoniae, a notorious human pathogen, is responsible for severe antibiotic-r...

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Detalles Bibliográficos
Autores principales: Milly, Tahmina A., Buttner, Alec R., Rieth, Naomi, Hutnick, Elizabeth, Engler, Emilee R., Campanella, Alexandra R., Lella, Muralikrishna, Bertucci, Michael A., Tal-Gan, Yftah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905529/
https://www.ncbi.nlm.nih.gov/pubmed/35359494
http://dx.doi.org/10.1039/d1cb00224d

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