Inner residues of macrothiolactone in autoinducer peptides I/IV circumvent spontaneous S-to-O acyl transfer to the upstream serine residue

Autoinducing peptides I and IV (AIP-I/IV) are naturally occurring cyclic thiodepsipeptides (CTPs) bearing a Ser–Thr–Cys–Asp/Tyr (STC[D/Y]) tetrapeptide motif, where the Cys thiol ((HS)C) in the side-chain is linked to the Met C-terminal carboxylic acid (M(COOH)) to form 5-residue macrothiolactones,(...

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Detalles Bibliográficos
Autores principales: Nagano, Masanobu, Ishida, Satoshi, Suga, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905530/
https://www.ncbi.nlm.nih.gov/pubmed/35359496
http://dx.doi.org/10.1039/d1cb00225b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905530/
https://www.ncbi.nlm.nih.gov/pubmed/35359496
http://dx.doi.org/10.1039/d1cb00225b

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