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Inner residues of macrothiolactone in autoinducer peptides I/IV circumvent spontaneous S-to-O acyl transfer to the upstream serine residue
Autoinducing peptides I and IV (AIP-I/IV) are naturally occurring cyclic thiodepsipeptides (CTPs) bearing a Ser–Thr–Cys–Asp/Tyr (STC[D/Y]) tetrapeptide motif, where the Cys thiol ((HS)C) in the side-chain is linked to the Met C-terminal carboxylic acid (M(COOH)) to form 5-residue macrothiolactones,(...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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RSC
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905530/ https://www.ncbi.nlm.nih.gov/pubmed/35359496 http://dx.doi.org/10.1039/d1cb00225b |