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Ketoconazole- and Metyrapone-Induced Reductions on Urinary Steroid Metabolites Alter the Urinary Free Cortisol Immunoassay Reliability in Cushing Syndrome
INTRODUCTION: Twenty-four-hour urinary free cortisol (24h-UFC) is the most used test for follow-up decision-making in patients with Cushing syndrome (CS) under medical treatment. However, 24h-UFC determinations by immunoassays (IA) are commonly overestimated because of steroid metabolites’ cross-rea...
Autores principales: | Vega-Beyhart, Arturo, Laguna-Moreno, Javier, Díaz-Catalán, Daniela, Boswell, Laura, Mora, Mireia, Halperin, Irene, Casals, Gregori, Hanzu, Felicia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905543/ https://www.ncbi.nlm.nih.gov/pubmed/35282465 http://dx.doi.org/10.3389/fendo.2022.833644 |
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