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Pharmacokinetic Modeling of [(11)C]GSK-189254, PET Tracer Targeting H(3) Receptors, in Rat Brain

[Image: see text] The histamine H(3) receptor has been considered as a target for the treatment of various central nervous system diseases. Positron emission tomography (PET) studies with the radiolabeled potent and selective histamine H(3) receptor antagonist [(11)C]GSK-189254 in rodents could be u...

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Detalles Bibliográficos
Autores principales:	Ghazanfari, Nafiseh, van Waarde, Aren, Doorduin, Janine, Sijbesma, Jürgen W. A., Kominia, Maria, Koelewijn, Martin, Attia, Khaled, Willemsen, Antoon T. M., Visser, Ton J., Heeres, André, Dierckx, Rudi A. J. O., de Vries, Erik F. J., Elsinga, Philip H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905578/ https://www.ncbi.nlm.nih.gov/pubmed/35170965 http://dx.doi.org/10.1021/acs.molpharmaceut.1c00889

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