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Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19
The impact of gut as the origin of different disorders has led to the "gut-origin concept" of diseases. The gut microbiome regulates host defenses against viral infections, thus dysbiosis can play a major role in triggering the cascade of inflammation and causing immune imbalances in COVID...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences (TUOMS Publishing Group)
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905593/ https://www.ncbi.nlm.nih.gov/pubmed/35411301 http://dx.doi.org/10.34172/bi.2021.42 |
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author | Mahmoodpoor, Ata Shamekh, Ali Sanaie, Sarvin |
author_facet | Mahmoodpoor, Ata Shamekh, Ali Sanaie, Sarvin |
author_sort | Mahmoodpoor, Ata |
collection | PubMed |
description | The impact of gut as the origin of different disorders has led to the "gut-origin concept" of diseases. The gut microbiome regulates host defenses against viral infections, thus dysbiosis can play a major role in triggering the cascade of inflammation and causing immune imbalances in COVID-19 patients. It appears that gut microbial signature in COVID-19 patients can be used as a potential diagnostic, therapeutic, and even a prognostic marker. Personalized nutrition therapy can be used by profiling the gut microbiota of individual patients and specialized probiotics/synbiotics to modify gut dysbiosis. Hence, improving overall immune responses can be recommended in these patients. |
format | Online Article Text |
id | pubmed-8905593 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Tabriz University of Medical Sciences (TUOMS Publishing Group) |
record_format | MEDLINE/PubMed |
spelling | pubmed-89055932022-04-10 Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 Mahmoodpoor, Ata Shamekh, Ali Sanaie, Sarvin Bioimpacts Letter to the Editor The impact of gut as the origin of different disorders has led to the "gut-origin concept" of diseases. The gut microbiome regulates host defenses against viral infections, thus dysbiosis can play a major role in triggering the cascade of inflammation and causing immune imbalances in COVID-19 patients. It appears that gut microbial signature in COVID-19 patients can be used as a potential diagnostic, therapeutic, and even a prognostic marker. Personalized nutrition therapy can be used by profiling the gut microbiota of individual patients and specialized probiotics/synbiotics to modify gut dysbiosis. Hence, improving overall immune responses can be recommended in these patients. Tabriz University of Medical Sciences (TUOMS Publishing Group) 2022 2021-08-30 /pmc/articles/PMC8905593/ /pubmed/35411301 http://dx.doi.org/10.34172/bi.2021.42 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc/4.0/ This work is published by BioImpacts as an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ). Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Letter to the Editor Mahmoodpoor, Ata Shamekh, Ali Sanaie, Sarvin Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 |
title | Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 |
title_full | Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 |
title_fullStr | Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 |
title_full_unstemmed | Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 |
title_short | Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 |
title_sort | gut microbial signature and gut-lung axis: a possible role in the therapy of covid-19 |
topic | Letter to the Editor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905593/ https://www.ncbi.nlm.nih.gov/pubmed/35411301 http://dx.doi.org/10.34172/bi.2021.42 |
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