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Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19

The impact of gut as the origin of different disorders has led to the "gut-origin concept" of diseases. The gut microbiome regulates host defenses against viral infections, thus dysbiosis can play a major role in triggering the cascade of inflammation and causing immune imbalances in COVID...

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Detalles Bibliográficos
Autores principales: Mahmoodpoor, Ata, Shamekh, Ali, Sanaie, Sarvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences (TUOMS Publishing Group) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905593/
https://www.ncbi.nlm.nih.gov/pubmed/35411301
http://dx.doi.org/10.34172/bi.2021.42
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author Mahmoodpoor, Ata
Shamekh, Ali
Sanaie, Sarvin
author_facet Mahmoodpoor, Ata
Shamekh, Ali
Sanaie, Sarvin
author_sort Mahmoodpoor, Ata
collection PubMed
description The impact of gut as the origin of different disorders has led to the "gut-origin concept" of diseases. The gut microbiome regulates host defenses against viral infections, thus dysbiosis can play a major role in triggering the cascade of inflammation and causing immune imbalances in COVID-19 patients. It appears that gut microbial signature in COVID-19 patients can be used as a potential diagnostic, therapeutic, and even a prognostic marker. Personalized nutrition therapy can be used by profiling the gut microbiota of individual patients and specialized probiotics/synbiotics to modify gut dysbiosis. Hence, improving overall immune responses can be recommended in these patients.
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spelling pubmed-89055932022-04-10 Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 Mahmoodpoor, Ata Shamekh, Ali Sanaie, Sarvin Bioimpacts Letter to the Editor The impact of gut as the origin of different disorders has led to the "gut-origin concept" of diseases. The gut microbiome regulates host defenses against viral infections, thus dysbiosis can play a major role in triggering the cascade of inflammation and causing immune imbalances in COVID-19 patients. It appears that gut microbial signature in COVID-19 patients can be used as a potential diagnostic, therapeutic, and even a prognostic marker. Personalized nutrition therapy can be used by profiling the gut microbiota of individual patients and specialized probiotics/synbiotics to modify gut dysbiosis. Hence, improving overall immune responses can be recommended in these patients. Tabriz University of Medical Sciences (TUOMS Publishing Group) 2022 2021-08-30 /pmc/articles/PMC8905593/ /pubmed/35411301 http://dx.doi.org/10.34172/bi.2021.42 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc/4.0/ This work is published by BioImpacts as an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Letter to the Editor
Mahmoodpoor, Ata
Shamekh, Ali
Sanaie, Sarvin
Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19
title Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19
title_full Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19
title_fullStr Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19
title_full_unstemmed Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19
title_short Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19
title_sort gut microbial signature and gut-lung axis: a possible role in the therapy of covid-19
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905593/
https://www.ncbi.nlm.nih.gov/pubmed/35411301
http://dx.doi.org/10.34172/bi.2021.42
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