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Pentamidine Alleviates Inflammation and Lipopolysaccharide-Induced Sepsis by Inhibiting TLR4 Activation via Targeting MD2

Toll-like receptor 4 (TLR4) is a pattern-recognition receptor (PRR) that can recognize lipopolysaccharides (LPS) and initiate the immune response, to protect the body from infection. However, excessive activation of TLR4 induced by LPS leads to substantial release of pro-inflammatory factors, which...

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Detalles Bibliográficos
Autores principales:	Wu, Siru, Lin, Cong, Zhang, Tianshu, Zhang, Bo, Jin, Yushan, Wang, Hongshuang, Li, Hongyuan, Wang, Yibo, Wang, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905599/ https://www.ncbi.nlm.nih.gov/pubmed/35281916 http://dx.doi.org/10.3389/fphar.2022.835081

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