An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes

Genetic manipulation of primary lymphocytes is crucial for both clinical purposes and fundamental research. Despite their broad use, we encountered a paucity of data on systematic comparison and optimization of retroviral vectors, the workhorses of genetic modification of primary lymphocytes. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Donk, Lieve E. H., van der Spek, Jet, van Duivenvoorde, Tom, ten Brink, Marieke S., Geijtenbeek, Teunis B. H., Kuijl, Coenraad P., van Heijst, Jeroen W. J., Ates, Louis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Methods & Techniques
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905627/
https://www.ncbi.nlm.nih.gov/pubmed/35229875
http://dx.doi.org/10.1242/bio.059032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905627/
https://www.ncbi.nlm.nih.gov/pubmed/35229875
http://dx.doi.org/10.1242/bio.059032

Ejemplares similares