Cargando…

Identification of Conserved Epitopes in SARS-CoV-2 Spike and Nucleocapsid Protein

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel virus that first occurred in Wuhan in December 2019. The spike glycoproteins and nucleocapsid proteins are the most common targets for the development of vaccines and antiviral drugs. OBJECTIVE: We herein analyze the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Forcelloni, Sergio, Benedetti, Anna, Dilucca, Maddalena, Giansanti, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905637/ https://www.ncbi.nlm.nih.gov/pubmed/35386436 http://dx.doi.org/10.2174/1389202923666211216162605

Ejemplares similares

Codon Usage and Phenotypic Divergences of SARS-CoV-2 Genes
por: Dilucca, Maddalena, et al.
Publicado: (2020)

Identification of SARS-CoV-2 Nucleocapsid and Spike T-Cell Epitopes for Assessing T-Cell Immunity
por: Lee, Eunok, et al.
Publicado: (2021)

The Epitope Study on the SARS-CoV Nucleocapsid Protein
por: Li, Shuting, et al.
Publicado: (2003)

Bioinformatics prediction of B and T cell epitopes within the spike and nucleocapsid proteins of SARS-CoV2
por: Dawood, Reham M., et al.
Publicado: (2021)

Identification of B-Cell Linear Epitopes in the Nucleocapsid (N) Protein B-Cell Linear Epitopes Conserved among the Main SARS-CoV-2 Variants
por: Rodrigues-da-Silva, Rodrigo N., et al.
Publicado: (2023)

Antibody detection of SARS-CoV spike and nucleocapsid protein
por: Chang, Mau-Sun, et al.
Publicado: (2004)

Bacterial Protein Interaction Networks: Connectivity is Ruled by Gene Conservation, Essentiality and Function
por: Dilucca, Maddalena, et al.
Publicado: (2021)

Identification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein
por: Jiang, Sheng, et al.
Publicado: (2022)

Identification of three conserved linear B cell epitopes on the SARS-CoV-2 spike protein
por: Wang, Aiping, et al.
Publicado: (2022)

Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity
por: Amrun, Siti Naqiah, et al.
Publicado: (2020)

Identification of two antigenic epitopes on SARS-CoV spike protein
por: Hua, Ronghong, et al.
Publicado: (2004)

Human CD4(+) T cells specific for dominant epitopes of SARS‐CoV‐2 Spike and Nucleocapsid proteins with therapeutic potential
por: Verhagen, Johan, et al.
Publicado: (2021)

Rapid Biosensor of SARS-CoV-2 Using Specific Monoclonal Antibodies Recognizing Conserved Nucleocapsid Protein Epitopes
por: Lee, Jong-Hwan, et al.
Publicado: (2022)

Performance of nucleocapsid and spike-based SARS-CoV-2 serologic assays
por: Rikhtegaran Tehrani, Zahra, et al.
Publicado: (2020)

Substitutions in Spike and Nucleocapsid proteins of SARS-CoV-2 circulating in South America
por: Franco-Muñoz, Carlos, et al.
Publicado: (2020)

Identification of a novel conserved HLA-A*0201-restricted epitope from the spike protein of SARS-CoV
por: Lv, Yanbo, et al.
Publicado: (2009)

Exploring the Immunodominant Epitopes of SARS-CoV-2 Nucleocapsid Protein as Exposure Biomarker
por: Vashisht, Kapil, et al.
Publicado: (2023)

Screening and identification of B cell epitope of the nucleocapsid protein in SARS-CoV-2 using the monoclonal antibodies
por: Tian, Yuanyuan, et al.
Publicado: (2022)

Peptidome Surveillance Across Evolving SARS-CoV-2 Lineages Reveals HLA Binding Conservation in Nucleocapsid Among Variants With Most Potential for T-Cell Epitope Loss in Spike
por: Wnuk, Kamil, et al.
Publicado: (2022)

Identification of an epitope of SARS-coronavirus nucleocapsid protein
por: LIN, Ying, et al.
Publicado: (2003)

Mutations in disordered proteins as early indicators of nucleic acid changes triggering speciation
por: Forcelloni, Sergio, et al.
Publicado: (2020)

Specificity and Performance of Nucleocapsid and Spike-based SARS-CoV-2 Serologic Assays
por: Tehrani, Zahra Rikhtegaran, et al.
Publicado: (2020)

Computational studies of the dynamics of SARS-CoV-2 spike, membrane, and nucleocapsid proteins
por: Dutta, Mandira, et al.
Publicado: (2022)

Detection of SARS-CoV-2 Nucleocapsid, Spike, and Neutralizing Antibodies in Vaccinated Japanese
por: Midorikawa, Rie, et al.
Publicado: (2022)

Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins
por: Wang, Zijun, et al.
Publicado: (2022)

Comparative computational analysis of SARS-CoV-2 nucleocapsid protein epitopes in taxonomically related coronaviruses
por: Tilocca, Bruno, et al.
Publicado: (2020)

In-silico design of a multi-epitope for developing sero-diagnosis detection of SARS-CoV-2 using spike glycoprotein and nucleocapsid antigens
por: Javadi Mamaghani, Amirreza, et al.
Publicado: (2021)

An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif
por: Fang, Yan, et al.
Publicado: (2022)

Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients
por: Lu, Xiuyuan, et al.
Publicado: (2021)

Human post‐infection serological response to the spike and nucleocapsid proteins of SARS‐CoV‐2
por: Xiao, Cheng, et al.
Publicado: (2020)

Combining spike- and nucleocapsid-based vaccines improves distal control of SARS-CoV-2
por: Dangi, Tanushree, et al.
Publicado: (2021)

Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation
por: Youn, Young-Jin, et al.
Publicado: (2021)

Cytotoxic T lymphocytes targeting a conserved SARS-CoV-2 spike epitope are efficient serial killers
por: Fathi, Mohsen, et al.
Publicado: (2022)

Computational epitope map of SARS-CoV-2 spike protein
por: Sikora, Mateusz, et al.
Publicado: (2021)

Highly specific monoclonal antibodies and epitope identification against SARS-CoV-2 nucleocapsid protein for antigen detection tests
por: Yamaoka, Yutaro, et al.
Publicado: (2021)

Immunoinformatics Study of SARS-CoV-2 Nucleocapsid Phosphoprotein Identifies Promising Epitopes with Mutational Implications
por: Kumar, S., et al.
Publicado: (2023)

Mutation profile of SARS-CoV-2 spike protein and identification of potential multiple epitopes within spike protein for vaccine development against SARS-CoV-2
por: Paul, Debadrita, et al.
Publicado: (2021)

Codon usage bias and environmental adaptation in microbial organisms
por: Arella, Davide, et al.
Publicado: (2021)

Novel antibody epitopes dominate the antigenicity of spike glycoprotein in SARS-CoV-2 compared to SARS-CoV
por: Zheng, Ming, et al.
Publicado: (2020)

Electrostatic features for nucleocapsid proteins of SARS-CoV and SARS-CoV-2
por: Guo, Wenhan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_051ird2rd0oob74lub99fj2pcs