Pilot study of repeated blood-brain barrier disruption in patients with mild Alzheimer’s disease with an implantable ultrasound device

BACKGROUND: Temporary disruption of the blood-brain barrier (BBB) using pulsed ultrasound leads to the clearance of both amyloid and tau from the brain, increased neurogenesis, and mitigation of cognitive decline in pre-clinical models of Alzheimer’s disease (AD) while also increasing BBB penetratio...

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Detalles Bibliográficos
Autores principales: Epelbaum, Stéphane, Burgos, Ninon, Canney, Michael, Matthews, Dawn, Houot, Marion, Santin, Mathieu D., Desseaux, Carole, Bouchoux, Guillaume, Stroer, Sebastian, Martin, Cyril, Habert, Marie-Odile, Levy, Marcel, Bah, Aicha, Martin, Karine, Delatour, Benoît, Riche, Maximilien, Dubois, Bruno, Belin, Lisa, Carpentier, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905724/
https://www.ncbi.nlm.nih.gov/pubmed/35260178
http://dx.doi.org/10.1186/s13195-022-00981-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905724/
https://www.ncbi.nlm.nih.gov/pubmed/35260178
http://dx.doi.org/10.1186/s13195-022-00981-1

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