Ceria-Zirconia nanoparticles reduce intracellular globotriaosylceramide accumulation and attenuate kidney injury by enhancing the autophagy flux in cellular and animal models of Fabry disease

BACKGROUND: Fabry disease (FD) is a lysosome storage disease (LSD) characterized by significantly reduced intracellular autophagy function. This contributes to the progression of intracellular pathologic signaling and can lead to organ injury. Phospholipid–polyethyleneglycol-capped Ceria-Zirconia an...

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Detalles Bibliográficos
Autores principales: An, Jong Hun, Hong, Sang-Eun, Yu, Seong-Lan, Kang, Jaeku, Park, Chang Gyo, Lee, Hoi Young, Lee, Sung-Ki, Lee, Dong Chul, Park, Hwan-Woo, Hwang, Won-Min, Yun, Sung-Ro, Park, Yohan, Park, Moon Hyang, Yoon, Kuk Ro, Yoon, Se-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905732/
https://www.ncbi.nlm.nih.gov/pubmed/35264192
http://dx.doi.org/10.1186/s12951-022-01318-8

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