Cur@SF NPs alleviate Friedreich’s ataxia in a mouse model through synergistic iron chelation and antioxidation

Abnormal iron metabolism, mitochondrial dysfunction and the derived oxidative damage are the main pathogeneses of Friedrich's ataxia (FRDA), a single-gene inherited recessive neurodegenerative disease characterized by progressive cerebellar and sensory ataxia. This disease is caused by frataxin...

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Detalles Bibliográficos
Autores principales: Xu, Li, Sun, Zichen, Xing, Zhiyao, Liu, Yutong, Zhao, Hongting, Tang, Zhongmin, Luo, Yu, Hao, Shuangying, Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905737/
https://www.ncbi.nlm.nih.gov/pubmed/35264205
http://dx.doi.org/10.1186/s12951-022-01333-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905737/
https://www.ncbi.nlm.nih.gov/pubmed/35264205
http://dx.doi.org/10.1186/s12951-022-01333-9

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