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Severe α(1)-antitrypsin deficiency associated with lower blood pressure and reduced risk of ischemic heart disease: a cohort study of 91,540 individuals and a meta-analysis
BACKGROUND: Increased elastase activity in α(1)-antitrypsin deficiency may affect elasticity of the arterial walls, and thereby blood pressure and susceptibility to cardiovascular disease. We hypothesized that severe α(1)-antitrypsin deficiency is associated with reduced blood pressure and susceptib...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905778/ https://www.ncbi.nlm.nih.gov/pubmed/35264159 http://dx.doi.org/10.1186/s12931-022-01973-3 |