Severe α(1)-antitrypsin deficiency associated with lower blood pressure and reduced risk of ischemic heart disease: a cohort study of 91,540 individuals and a meta-analysis

BACKGROUND: Increased elastase activity in α(1)-antitrypsin deficiency may affect elasticity of the arterial walls, and thereby blood pressure and susceptibility to cardiovascular disease. We hypothesized that severe α(1)-antitrypsin deficiency is associated with reduced blood pressure and susceptib...

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Detalles Bibliográficos
Autores principales: Winther, Sine Voss, Ahmed, Dunia, Al-Shuweli, Suzan, Landt, Eskild Morten, Nordestgaard, Børge Grønne, Seersholm, Niels, Dahl, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905778/
https://www.ncbi.nlm.nih.gov/pubmed/35264159
http://dx.doi.org/10.1186/s12931-022-01973-3

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