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Neuron secrete exosomes containing miR-9-5p to promote polarization of M1 microglia in depression

BACKGROUND: Neuroinflammation is an important component mechanism in the development of depression. Exosomal transfer of MDD-associated microRNAs (miRNAs) from neurons to microglia might exacerbate neuronal cell inflammatory injury. RESULTS: By sequence identification, we found significantly higher...

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Detalles Bibliográficos
Autores principales:	Xian, Xian, Cai, Li-Li, Li, Yang, Wang, Ran-Chao, Xu, Yu-Hao, Chen, Ya-Jie, Xie, Yu-Hang, Zhu, Xiao-Lan, Li, Yue-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905830/ https://www.ncbi.nlm.nih.gov/pubmed/35264203 http://dx.doi.org/10.1186/s12951-022-01332-w

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