Novel sequential therapy with metformin enhances the effects of cisplatin in testicular germ cell tumours via YAP1 signalling

BACKGROUND: Testicular germ cell tumours (TGCTs) are the most commonly diagnosed malignancy in young men. Although cisplatin has been shown to be effective to treat TGCT patients, long-term follow-up has shown that TGCT survivors who accepted cisplatin treatment suffered from a greater number of adv...

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Detalles Bibliográficos
Autores principales: He, Kancheng, Li, Zitaiyu, Ye, Kun, Zhou, Yihong, Yan, Minbo, Qi, Hao, Hu, Huating, Dai, Yingbo, Tang, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905836/
https://www.ncbi.nlm.nih.gov/pubmed/35264157
http://dx.doi.org/10.1186/s12935-022-02534-w

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