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Mechanistic insights into the C(55)-P targeting lipopeptide antibiotics revealed by structure–activity studies and high-resolution crystal structures
The continued rise of antibiotic resistance is a global concern that threatens to undermine many aspects of modern medical practice. Key to addressing this threat is the discovery and development of new antibiotics that operate by unexploited modes of action. The so-called calcium-dependent lipopept...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905900/ https://www.ncbi.nlm.nih.gov/pubmed/35382464 http://dx.doi.org/10.1039/d1sc07190d |