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Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis

BACKGROUND: Postpartum hemorrhage or postpartum bleeding (PPH) is often defined as loss of > 500 ml of blood after vaginal delivery or > 1000 ml after cesarean delivery within 24 h. Postpartum hemorrhage is a leading direct cause of maternal morbidity and mortality in Ethiopia. Therefore, the...

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Autores principales: Nigussie, Jemberu, Girma, Bekahegn, Molla, Alemayehu, Tamir, Takla, Tilahun, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905908/
https://www.ncbi.nlm.nih.gov/pubmed/35264188
http://dx.doi.org/10.1186/s12978-022-01360-7
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author Nigussie, Jemberu
Girma, Bekahegn
Molla, Alemayehu
Tamir, Takla
Tilahun, Ruth
author_facet Nigussie, Jemberu
Girma, Bekahegn
Molla, Alemayehu
Tamir, Takla
Tilahun, Ruth
author_sort Nigussie, Jemberu
collection PubMed
description BACKGROUND: Postpartum hemorrhage or postpartum bleeding (PPH) is often defined as loss of > 500 ml of blood after vaginal delivery or > 1000 ml after cesarean delivery within 24 h. Postpartum hemorrhage is a leading direct cause of maternal morbidity and mortality in Ethiopia. Therefore, the main objective of this systematic review and meta-analysis was to estimate the pooled magnitude of postpartum hemorrhage and the pooled effect size of the associated factors in Ethiopia. METHODS: Primary studies were searched from PubMed/MEDLINE online, Science Direct, Hinari, Cochrane Library, CINAHL, African Journals Online, Google and Google Scholars databases. The searching of the primary studies included for this systematic review and meta-analysis was limited by papers published from 2010 to October 10/2021. The data extraction format was prepared in Microsoft Excel and extracted data was exported to Stata Version 16.0 statistical software for analysis. A random effect meta-analysis model was used. Statistical heterogeneity was evaluated by the I(2) test and Egger’s weighted regression test was used to assess publication bias. RESULT: A total of 21 studies were included in this meta-analysis. The pooled magnitude of postpartum hemorrhage in Ethiopia was 8.24% [(95% CI 7.07, 9.40]. Older age [OR = 5.038 (95% CI 2.774, 9.151)], prolonged labor [OR = 4.054 (95% CI 1.484, 11.074)], absence of anti-natal care visits (ANC) [OR = 13.84 (95% CI 5.57, 34.346)], grand-multiparty [OR = 6.584 (95% CI 1.902, 22.795)], and history of postpartum hemorrhage [OR = 4.355 (95% CI 2.347, 8.079)] were factors associated with the occurrence of postpartum hemorrhage. CONCLUSIONS: The pooled magnitude of postpartum hemorrhage among post-natal mothers in Ethiopia was moderately high. The finding of this study will strongly help different stakeholder working in maternal and child health to focus on the main contributors’ factors to reduce post-partum hemorrhage among postnatal mothers. Health professionals attending labor and delivery should give more attention to advanced aged mothers, grand-multipara mothers and mothers who had a history of post-partum hemorrhage due to higher risk for postpartum hemorrhage. Encouraging to continue ANC visit and prevent prolonged labor should also be recommended to decrease postpartum hemorrhage. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12978-022-01360-7.
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spelling pubmed-89059082022-03-18 Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis Nigussie, Jemberu Girma, Bekahegn Molla, Alemayehu Tamir, Takla Tilahun, Ruth Reprod Health Research BACKGROUND: Postpartum hemorrhage or postpartum bleeding (PPH) is often defined as loss of > 500 ml of blood after vaginal delivery or > 1000 ml after cesarean delivery within 24 h. Postpartum hemorrhage is a leading direct cause of maternal morbidity and mortality in Ethiopia. Therefore, the main objective of this systematic review and meta-analysis was to estimate the pooled magnitude of postpartum hemorrhage and the pooled effect size of the associated factors in Ethiopia. METHODS: Primary studies were searched from PubMed/MEDLINE online, Science Direct, Hinari, Cochrane Library, CINAHL, African Journals Online, Google and Google Scholars databases. The searching of the primary studies included for this systematic review and meta-analysis was limited by papers published from 2010 to October 10/2021. The data extraction format was prepared in Microsoft Excel and extracted data was exported to Stata Version 16.0 statistical software for analysis. A random effect meta-analysis model was used. Statistical heterogeneity was evaluated by the I(2) test and Egger’s weighted regression test was used to assess publication bias. RESULT: A total of 21 studies were included in this meta-analysis. The pooled magnitude of postpartum hemorrhage in Ethiopia was 8.24% [(95% CI 7.07, 9.40]. Older age [OR = 5.038 (95% CI 2.774, 9.151)], prolonged labor [OR = 4.054 (95% CI 1.484, 11.074)], absence of anti-natal care visits (ANC) [OR = 13.84 (95% CI 5.57, 34.346)], grand-multiparty [OR = 6.584 (95% CI 1.902, 22.795)], and history of postpartum hemorrhage [OR = 4.355 (95% CI 2.347, 8.079)] were factors associated with the occurrence of postpartum hemorrhage. CONCLUSIONS: The pooled magnitude of postpartum hemorrhage among post-natal mothers in Ethiopia was moderately high. The finding of this study will strongly help different stakeholder working in maternal and child health to focus on the main contributors’ factors to reduce post-partum hemorrhage among postnatal mothers. Health professionals attending labor and delivery should give more attention to advanced aged mothers, grand-multipara mothers and mothers who had a history of post-partum hemorrhage due to higher risk for postpartum hemorrhage. Encouraging to continue ANC visit and prevent prolonged labor should also be recommended to decrease postpartum hemorrhage. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12978-022-01360-7. BioMed Central 2022-03-09 /pmc/articles/PMC8905908/ /pubmed/35264188 http://dx.doi.org/10.1186/s12978-022-01360-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Nigussie, Jemberu
Girma, Bekahegn
Molla, Alemayehu
Tamir, Takla
Tilahun, Ruth
Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis
title Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis
title_full Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis
title_fullStr Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis
title_full_unstemmed Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis
title_short Magnitude of postpartum hemorrhage and its associated factors in Ethiopia: a systematic review and meta-analysis
title_sort magnitude of postpartum hemorrhage and its associated factors in ethiopia: a systematic review and meta-analysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905908/
https://www.ncbi.nlm.nih.gov/pubmed/35264188
http://dx.doi.org/10.1186/s12978-022-01360-7
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