Cargando…
Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine
A 14-year-old boy was referred to the ophthalmology department with a 4-day history of rapid-onset right upper lid pain, swelling and erythema starting 9 hours after his first dose of COVID-19 mRNA vaccination (BNT162b2/Comirnaty, Pfizer-BioNTech). On examination, he had significant right upper lid...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905968/ https://www.ncbi.nlm.nih.gov/pubmed/35256374 http://dx.doi.org/10.1136/bcr-2021-248441 |
_version_ | 1784665302785589248 |
---|---|
author | Murphy, Treasa Raheem Abu Shanab, Abdul Kang, Kristopher Lyons, Christopher J |
author_facet | Murphy, Treasa Raheem Abu Shanab, Abdul Kang, Kristopher Lyons, Christopher J |
author_sort | Murphy, Treasa |
collection | PubMed |
description | A 14-year-old boy was referred to the ophthalmology department with a 4-day history of rapid-onset right upper lid pain, swelling and erythema starting 9 hours after his first dose of COVID-19 mRNA vaccination (BNT162b2/Comirnaty, Pfizer-BioNTech). On examination, he had significant right upper lid ptosis, oedema and erythema, with associated limitation of right eye abduction and elevation. He was found to have acute dacryoadenitis with orbital inflammatory disease on clinical and laboratory investigations. He was given tapering oral prednisone and had full resolution of symptoms within 2 weeks. This is the first known case of orbital inflammation after COVID-19 mRNA vaccination. Given the temporal association between the patient’s vaccination and symptom onset, we believe it is likely that immunisation prompted the onset of disease. |
format | Online Article Text |
id | pubmed-8905968 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-89059682022-03-25 Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine Murphy, Treasa Raheem Abu Shanab, Abdul Kang, Kristopher Lyons, Christopher J BMJ Case Rep Case Reports: Adverse drug reactions and complications A 14-year-old boy was referred to the ophthalmology department with a 4-day history of rapid-onset right upper lid pain, swelling and erythema starting 9 hours after his first dose of COVID-19 mRNA vaccination (BNT162b2/Comirnaty, Pfizer-BioNTech). On examination, he had significant right upper lid ptosis, oedema and erythema, with associated limitation of right eye abduction and elevation. He was found to have acute dacryoadenitis with orbital inflammatory disease on clinical and laboratory investigations. He was given tapering oral prednisone and had full resolution of symptoms within 2 weeks. This is the first known case of orbital inflammation after COVID-19 mRNA vaccination. Given the temporal association between the patient’s vaccination and symptom onset, we believe it is likely that immunisation prompted the onset of disease. BMJ Publishing Group 2022-03-07 /pmc/articles/PMC8905968/ /pubmed/35256374 http://dx.doi.org/10.1136/bcr-2021-248441 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ. |
spellingShingle | Case Reports: Adverse drug reactions and complications Murphy, Treasa Raheem Abu Shanab, Abdul Kang, Kristopher Lyons, Christopher J Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine |
title | Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine |
title_full | Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine |
title_fullStr | Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine |
title_full_unstemmed | Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine |
title_short | Acute-onset dacryoadenitis following immunisation with mRNA COVID-19 vaccine |
title_sort | acute-onset dacryoadenitis following immunisation with mrna covid-19 vaccine |
topic | Case Reports: Adverse drug reactions and complications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8905968/ https://www.ncbi.nlm.nih.gov/pubmed/35256374 http://dx.doi.org/10.1136/bcr-2021-248441 |
work_keys_str_mv | AT murphytreasa acuteonsetdacryoadenitisfollowingimmunisationwithmrnacovid19vaccine AT raheemabushanababdul acuteonsetdacryoadenitisfollowingimmunisationwithmrnacovid19vaccine AT kangkristopher acuteonsetdacryoadenitisfollowingimmunisationwithmrnacovid19vaccine AT lyonschristopherj acuteonsetdacryoadenitisfollowingimmunisationwithmrnacovid19vaccine |