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Transthyretin deposition alters cardiomyocyte sarcomeric architecture, calcium transients, and contractile force

Age‐related wild‐type transthyretin amyloidosis (wtATTR) is characterized by systemic deposition of amyloidogenic fibrils of misfolded transthyretin (TTR) in the connective tissue of many organs. In the heart, this leads to age‐related heart failure with preserved ejection fraction (HFpEF). The hypo...

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Detalles Bibliográficos
Autores principales:	Dittloff, Kyle T., Spanghero, Emanuele, Solís, Christopher, Banach, Kathrin, Russell, Brenda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906053/ https://www.ncbi.nlm.nih.gov/pubmed/35262277 http://dx.doi.org/10.14814/phy2.15207

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