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Label-free duplex SAMDI-MS screen reveals novel SARS-CoV-2 3CLpro inhibitors

The 3-chymotrypsin-like cysteine protease (3CLpro) of severe acute respiratory syndrome conoravirus 2 (SARS-CoV-2) remains a promising therapeutic target to combat COVID-19. Our group recently described a novel duplexed biochemical assay that combines self-assembled monolayers of alkanethiolates on...

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Detalles Bibliográficos
Autores principales:	Scholle, Michael D., O'Kane, Patrick T., Dib, Sandra, Gurard-Levin, Zachary A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906060/ https://www.ncbi.nlm.nih.gov/pubmed/35278580 http://dx.doi.org/10.1016/j.antiviral.2022.105279

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