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Combination of chemistry and material science to overcome health problems

Since its outbreak, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has strongly influenced the life of the general public around the world. Based on its fast spread and high mortality, there is a need for novel therapeutic treatments to overcome this global health crisis. While med...

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Autor principal: Karges, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Medical Association Publishing House. Published by Elsevier BV. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906073/
https://www.ncbi.nlm.nih.gov/pubmed/35284813
http://dx.doi.org/10.1016/j.bsheal.2022.03.004
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author Karges, Johannes
author_facet Karges, Johannes
author_sort Karges, Johannes
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description Since its outbreak, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has strongly influenced the life of the general public around the world. Based on its fast spread and high mortality, there is a need for novel therapeutic treatments to overcome this global health crisis. While medicinal chemistry is focused on the development of highly selective and affine inhibitors toward a specific target enzyme, material science is focused on the development of nanomaterials for selective drug delivery. Based on the individual strengths, these disciplines could synergistically act together and help overcome the limitations of the respective approach. Herein, the combination of medicinal chemistry with material science to overcome health problems with the example of SARS-CoV-2 is critically discussed.
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spelling pubmed-89060732022-03-09 Combination of chemistry and material science to overcome health problems Karges, Johannes Biosaf Health Article Since its outbreak, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has strongly influenced the life of the general public around the world. Based on its fast spread and high mortality, there is a need for novel therapeutic treatments to overcome this global health crisis. While medicinal chemistry is focused on the development of highly selective and affine inhibitors toward a specific target enzyme, material science is focused on the development of nanomaterials for selective drug delivery. Based on the individual strengths, these disciplines could synergistically act together and help overcome the limitations of the respective approach. Herein, the combination of medicinal chemistry with material science to overcome health problems with the example of SARS-CoV-2 is critically discussed. Chinese Medical Association Publishing House. Published by Elsevier BV. 2022-04 2022-03-09 /pmc/articles/PMC8906073/ /pubmed/35284813 http://dx.doi.org/10.1016/j.bsheal.2022.03.004 Text en © 2022 Chinese Medical Association Publishing House. Published by Elsevier BV. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Karges, Johannes
Combination of chemistry and material science to overcome health problems
title Combination of chemistry and material science to overcome health problems
title_full Combination of chemistry and material science to overcome health problems
title_fullStr Combination of chemistry and material science to overcome health problems
title_full_unstemmed Combination of chemistry and material science to overcome health problems
title_short Combination of chemistry and material science to overcome health problems
title_sort combination of chemistry and material science to overcome health problems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906073/
https://www.ncbi.nlm.nih.gov/pubmed/35284813
http://dx.doi.org/10.1016/j.bsheal.2022.03.004
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