A case of CRPC with multiple bladder invasions treated with EBRT followed by HDR-BT boost

We report a case of post-operative local recurrence of castration-resistant prostate cancer with multiple bulky bladder invasions treated using external beam radiotherapy (EBRT) followed by a high-dose-rate brachytherapy (HDR-BT) boost. The EBRT dose was 46 Gy delivered in 23 fractions with intensit...

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Detalles Bibliográficos
Autores principales: Takagawa, Yoshiaki, Itami, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906154/
https://www.ncbi.nlm.nih.gov/pubmed/35300242
http://dx.doi.org/10.1259/bjrcr.20210039
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author Takagawa, Yoshiaki
Itami, Jun
author_facet Takagawa, Yoshiaki
Itami, Jun
author_sort Takagawa, Yoshiaki
collection PubMed
description We report a case of post-operative local recurrence of castration-resistant prostate cancer with multiple bulky bladder invasions treated using external beam radiotherapy (EBRT) followed by a high-dose-rate brachytherapy (HDR-BT) boost. The EBRT dose was 46 Gy delivered in 23 fractions with intensity-modulated radiotherapy to the entire pelvis. The HDR-BT dose was 15 Gy delivered in 1 fraction using ultrasound, CT, and MRI-guided brachytherapy with 18 interstitial needles. We achieved excellent local control of cancer in the prostate bed and multiple bulky bladder invasions. EBRT plus HDR-BT boost can allow higher doses to be delivered than EBRT alone for locally recurrent bulky prostate cancer following prostatectomy.
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spelling pubmed-89061542022-03-16 A case of CRPC with multiple bladder invasions treated with EBRT followed by HDR-BT boost Takagawa, Yoshiaki Itami, Jun BJR Case Rep Case Report We report a case of post-operative local recurrence of castration-resistant prostate cancer with multiple bulky bladder invasions treated using external beam radiotherapy (EBRT) followed by a high-dose-rate brachytherapy (HDR-BT) boost. The EBRT dose was 46 Gy delivered in 23 fractions with intensity-modulated radiotherapy to the entire pelvis. The HDR-BT dose was 15 Gy delivered in 1 fraction using ultrasound, CT, and MRI-guided brachytherapy with 18 interstitial needles. We achieved excellent local control of cancer in the prostate bed and multiple bulky bladder invasions. EBRT plus HDR-BT boost can allow higher doses to be delivered than EBRT alone for locally recurrent bulky prostate cancer following prostatectomy. The British Institute of Radiology. 2022-03-09 /pmc/articles/PMC8906154/ /pubmed/35300242 http://dx.doi.org/10.1259/bjrcr.20210039 Text en © 2021 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Takagawa, Yoshiaki
Itami, Jun
A case of CRPC with multiple bladder invasions treated with EBRT followed by HDR-BT boost
title A case of CRPC with multiple bladder invasions treated with EBRT followed by HDR-BT boost
title_full A case of CRPC with multiple bladder invasions treated with EBRT followed by HDR-BT boost
title_fullStr A case of CRPC with multiple bladder invasions treated with EBRT followed by HDR-BT boost
title_full_unstemmed A case of CRPC with multiple bladder invasions treated with EBRT followed by HDR-BT boost
title_short A case of CRPC with multiple bladder invasions treated with EBRT followed by HDR-BT boost
title_sort case of crpc with multiple bladder invasions treated with ebrt followed by hdr-bt boost
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906154/
https://www.ncbi.nlm.nih.gov/pubmed/35300242
http://dx.doi.org/10.1259/bjrcr.20210039
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