Validation of DE50-MD dogs as a model for the brain phenotype of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD), a fatal musculoskeletal disease, is associated with neurodevelopmental disorders and cognitive impairment caused by brain dystrophin deficiency. Dog models of DMD represent key translational tools to study dystrophin biology and to develop novel therapeutics. Howev...

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Detalles Bibliográficos
Autores principales: Crawford, Abbe H., Hildyard, John C. W., Rushing, Sophie A. M., Wells, Dominic J., Diez-Leon, Maria, Piercy, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906169/
https://www.ncbi.nlm.nih.gov/pubmed/35019137
http://dx.doi.org/10.1242/dmm.049291

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