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A novel and efficient murine model of Bietti crystalline dystrophy
Bietti crystalline dystrophy (BCD) is an autosomal recessive inherited retinal disease, resulting in blindness in most patients. The etiology and development mechanism of it remain unclear. Given the defects in previous mouse models of BCD, we generated a new Cyp4v3(−/−) mouse model, using CRISPR/Ca...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906172/ https://www.ncbi.nlm.nih.gov/pubmed/35230417 http://dx.doi.org/10.1242/dmm.049222 |