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A novel and efficient murine model of Bietti crystalline dystrophy

Bietti crystalline dystrophy (BCD) is an autosomal recessive inherited retinal disease, resulting in blindness in most patients. The etiology and development mechanism of it remain unclear. Given the defects in previous mouse models of BCD, we generated a new Cyp4v3(−/−) mouse model, using CRISPR/Ca...

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Detalles Bibliográficos
Autores principales: Wang, Yafang, Liu, Yang, Liu, Shu, Li, Xiaomeng, Liu, Xinxin, Jiao, Ming, Yang, Yuqin, Luo, Xueting, Wang, Fenghua, Wan, Xiaoling, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906172/
https://www.ncbi.nlm.nih.gov/pubmed/35230417
http://dx.doi.org/10.1242/dmm.049222

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