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Analysis of CSF D-Dimer to Identify Intrathecal Fibrin-Driven Autoimmunity in Patients With Multiple Sclerosis

BACKGROUND AND OBJECTIVES: Proteins of the coagulation system contribute to autoimmune inflammation in patients with multiple sclerosis (MS). On blood-brain barrier (BBB) disruption, fibrinogen enters the CNS and is rapidly converted to fibrin, unfolding pleiotropic autoimmune mechanisms. Fibrin acc...

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Detalles Bibliográficos
Autores principales:	Schaller-Paule, Martin A., Yalachkov, Yavor, Steinmetz, Helmuth, Friedauer, Lucie, Hattingen, Elke, Miesbach, Wolfgang, Weber, Frank, Kirchmayr, Konstantin, Schaefer, Jan Hendrik, Foerch, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	RESEARCH Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906189/ https://www.ncbi.nlm.nih.gov/pubmed/35260469 http://dx.doi.org/10.1212/NXI.0000000000001150

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