Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

Recent emergence of SARS-CoV-1 variants demonstrates the potential of this virus for targeted evolution, despite its overall genomic stability. Here we show the dynamics and the mechanisms behind the rapid adaptation of SARS-CoV-2 to growth in Vero E6 cells. The selective advantage for growth in Ver...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaudhry, M. Zeeshan, Eschke, Kathrin, Hoffmann, Markus, Grashoff, Martina, Abassi, Leila, Kim, Yeonsu, Brunotte, Linda, Ludwig, Stephan, Kröger, Andrea, Klawonn, Frank, Pöhlmann, Stefan H., Cicin-Sain, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Genetic Diversity and Evolution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906416/
https://www.ncbi.nlm.nih.gov/pubmed/35019723
http://dx.doi.org/10.1128/jvi.02186-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906416/
https://www.ncbi.nlm.nih.gov/pubmed/35019723
http://dx.doi.org/10.1128/jvi.02186-21

Ejemplares similares