Cargando…

Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

Recent emergence of SARS-CoV-1 variants demonstrates the potential of this virus for targeted evolution, despite its overall genomic stability. Here we show the dynamics and the mechanisms behind the rapid adaptation of SARS-CoV-2 to growth in Vero E6 cells. The selective advantage for growth in Ver...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chaudhry, M. Zeeshan, Eschke, Kathrin, Hoffmann, Markus, Grashoff, Martina, Abassi, Leila, Kim, Yeonsu, Brunotte, Linda, Ludwig, Stephan, Kröger, Andrea, Klawonn, Frank, Pöhlmann, Stefan H., Cicin-Sain, Luka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906416/ https://www.ncbi.nlm.nih.gov/pubmed/35019723 http://dx.doi.org/10.1128/jvi.02186-21

Ejemplares similares

Long-term immune protection against SARS-CoV-2 escape variants upon a single vaccination with murine cytomegalovirus expressing the spike protein
por: Kim, Yeonsu, et al.
Publicado: (2022)

HIV-1 Protease, Reverse Transcriptase, and Integrase Variation
por: Rhee, Soo-Yon, et al.
Publicado: (2016)

Dengue virus serotypic replacement of NS3 protease or helicase domain causes chimeric viral attenuation but can be recovered by a compensated mutation at helicase domain or NS2B, respectively
por: Teramoto, Tadahisa
Publicado: (2023)

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination
por: Kim, Yeonsu, et al.
Publicado: (2022)

Unfixed Endogenous Retroviral Insertions in the Human Population
por: Marchi, Emanuele, et al.
Publicado: (2014)

Deep Sequencing of Norovirus Genomes Defines Evolutionary Patterns in an Urban Tropical Setting
por: Cotten, Matthew, et al.
Publicado: (2014)

Powerful Sequence Similarity Search Methods and In-Depth Manual Analyses Can Identify Remote Homologs in Many Apparently “Orphan” Viral Proteins
por: Kuchibhatla, Durga B., et al.
Publicado: (2014)

Stability of the Parainfluenza Virus 5 Genome Revealed by Deep Sequencing of Strains Isolated from Different Hosts and following Passage in Cell Culture
por: Rima, Bert K., et al.
Publicado: (2014)

Genome Diversity of Epstein-Barr Virus from Multiple Tumor Types and Normal Infection
por: Palser, Anne L., et al.
Publicado: (2015)

Local Evolutionary Patterns of Human Respiratory Syncytial Virus Derived from Whole-Genome Sequencing
por: Agoti, Charles N., et al.
Publicado: (2015)

Phylodynamics of Enterovirus A71-Associated Hand, Foot, and Mouth Disease in Viet Nam
por: Geoghegan, Jemma L., et al.
Publicado: (2015)

Sinorhizobium meliloti Phage ΦM9 Defines a New Group of T4 Superfamily Phages with Unusual Genomic Features but a Common T=16 Capsid
por: Johnson, Matthew C., et al.
Publicado: (2015)

Novel Denisovan and Neanderthal Retroviruses
por: Lee, Adam, et al.
Publicado: (2014)

Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom
por: Elderfield, Ruth A., et al.
Publicado: (2014)

Evolution of Cocirculating Varicella-Zoster Virus Genotypes during a Chickenpox Outbreak in Guinea-Bissau
por: Depledge, Daniel P., et al.
Publicado: (2014)

Molecular Evolutionary Dynamics of Respiratory Syncytial Virus Group A in Recurrent Epidemics in Coastal Kenya
por: Otieno, James R., et al.
Publicado: (2016)

Increasing Clinical Severity during a Dengue Virus Type 3 Cuban Epidemic: Deep Sequencing of Evolving Viral Populations
por: Rodriguez-Roche, Rosmari, et al.
Publicado: (2016)

Genetic Stability of Bacterial Artificial Chromosome-Derived Human Cytomegalovirus during Culture In Vitro
por: Murrell, Isa, et al.
Publicado: (2016)

Salmon Gill Poxvirus, the Deepest Representative of the Chordopoxvirinae
por: Gjessing, Mona C., et al.
Publicado: (2015)

Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013
por: Watson, Simon J., et al.
Publicado: (2015)

Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification
por: Li, Hui, et al.
Publicado: (2015)

Genetics, Receptor Binding, Replication, and Mammalian Transmission of H4 Avian Influenza Viruses Isolated from Live Poultry Markets in China
por: Liang, Libin, et al.
Publicado: (2016)

Spatial-Temporal Patterns of Viral Amplification and Interference Initiated by a Single Infected Cell
por: Akpinar, Fulya, et al.
Publicado: (2016)

Characterizing the Diverse Mutational Pathways Associated with R5-Tropic Maraviroc Resistance: HIV-1 That Uses the Drug-Bound CCR5 Coreceptor
por: Jiang, Xiaowei, et al.
Publicado: (2015)

Successive Respiratory Syncytial Virus Epidemics in Local Populations Arise from Multiple Variant Introductions, Providing Insights into Virus Persistence
por: Agoti, Charles N., et al.
Publicado: (2015)

Characterization of a Novel Hepadnavirus in the White Sucker (Catostomus commersonii) from the Great Lakes Region of the United States
por: Hahn, Cassidy M., et al.
Publicado: (2015)

Ecuador Paraiso Escondido Virus, a New Flavivirus Isolated from New World Sand Flies in Ecuador, Is the First Representative of a Novel Clade in the Genus Flavivirus
por: Alkan, Cigdem, et al.
Publicado: (2015)

Complete Unique Genome Sequence, Expression Profile, and Salivary Gland Tissue Tropism of the Herpesvirus 7 Homolog in Pigtailed Macaques
por: Staheli, Jeannette P., et al.
Publicado: (2016)

Time-Dependent Rate Phenomenon in Viruses
por: Aiewsakun, Pakorn, et al.
Publicado: (2016)

Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification
por: Sobel Leonard, Ashley, et al.
Publicado: (2016)

Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica
por: Hurt, Aeron C., et al.
Publicado: (2016)

Characterization of Clade 7.2 H5 Avian Influenza Viruses That Continue To Circulate in Chickens in China
por: Liu, Liling, et al.
Publicado: (2016)

Characterization of Equine Infectious Anemia Virus Long Terminal Repeat Quasispecies In Vitro and In Vivo
por: Wang, Xue-Feng, et al.
Publicado: (2018)

Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico
por: Soto-Nava, Maribel, et al.
Publicado: (2018)

Heterogeneity of the Epstein-Barr Virus (EBV) Major Internal Repeat Reveals Evolutionary Mechanisms of EBV and a Functional Defect in the Prototype EBV Strain B95-8
por: Ba abdullah, Mohammed M., et al.
Publicado: (2017)

Ancient Evolution and Dispersion of Human Papillomavirus 58 Variants
por: Chen, Zigui, et al.
Publicado: (2017)

Avian Influenza Viruses in Wild Birds: Virus Evolution in a Multihost Ecosystem
por: Venkatesh, Divya, et al.
Publicado: (2018)

Insights into Circovirus Host Range from the Genomic Fossil Record
por: Dennis, Tristan P. W., et al.
Publicado: (2018)

A Novel Marsupial Hepatitis A Virus Corroborates Complex Evolutionary Patterns Shaping the Genus Hepatovirus
por: de Oliveira Carneiro, Ianei, et al.
Publicado: (2018)

Whole-Genome Sequencing and Variant Analysis of Human Papillomavirus 16 Infections
por: van der Weele, Pascal, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_u6dq1r1daja2f1oij9tm59k4l6