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Virus-Like Particles Containing the E2 Core Domain of Hepatitis C Virus Generate Broadly Neutralizing Antibodies in Guinea Pigs

A vaccine to prevent hepatitis C virus (HCV) infection is urgently needed for use alongside direct-acting antiviral drugs to achieve elimination targets. We have previously shown that a soluble recombinant form of the glycoprotein E2 ectodomain (residues 384 to 661) that lacks three variable regions...

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Detalles Bibliográficos
Autores principales:	McGregor, Joey, Hardy, Joshua M., Lay, Chan-Sien, Boo, Irene, Piontek, Michael, Suckow, Manfred, Coulibaly, Fasséli, Poumbourios, Pantelis, Center, Rob J., Drummer, Heidi E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Vaccines and Antiviral Agents
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906423/ https://www.ncbi.nlm.nih.gov/pubmed/34986001 http://dx.doi.org/10.1128/jvi.01675-21

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