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Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection
Hepatitis B virus (HBV) infects 240 million people worldwide. Current therapy profoundly suppresses HBV replication but requires long-term maintenance therapy. Therefore, there is still a medical need for an efficient HBV cure. HBV enters host cells by binding via the preS1 domain of the viral L pro...
Autores principales: | Takemori, Toshitada, Sugimoto-Ishige, Akiko, Nishitsuji, Hironori, Futamura, Yushi, Harada, Michishige, Kimura-Someya, Tomomi, Matsumoto, Takehisa, Honma, Teruki, Tanaka, Miho, Yaguchi, Masami, Isono, Kyoichi, Koseki, Haruhiko, Osada, Hiroyuki, Miki, Daiki, Saito, Takashi, Tanaka, Takashi, Fukami, Takehiro, Goto, Toshio, Shirouzu, Mikako, Shimotohno, Kunitada, Chayama, Kazuaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906425/ https://www.ncbi.nlm.nih.gov/pubmed/34985994 http://dx.doi.org/10.1128/jvi.01686-21 |
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