Monocytic MDSCs homing to thymus contribute to age-related CD8(+) T cell tolerance of HBV

Hepatitis B virus exposure in children usually develops into chronic hepatitis B (CHB). Although hepatitis B surface antigen (HBsAg)–specific CD8(+) T cells contribute to resolve HBV infection, they are preferentially undetected in CHB patients. Moreover, the mechanism for this rarely detected HBsAg...

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Detalles Bibliográficos
Autores principales: Fang, Zhong, Zhang, Yi, Zhu, Zhaoqin, Wang, Cong, Hu, Yao, Peng, Xiuhua, Zhang, Dandan, Zhao, Jun, Shi, Bisheng, Shen, Zhongliang, Wu, Min, Xu, Chunhua, Chen, Jieliang, Zhou, Xiaohui, Xie, Youhua, Yu, Hui, Zhang, Xiaonan, Li, Jianhua, Hu, Yunwen, Kozlowski, Maya, Bertoletti, Antonio, Yuan, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906470/
https://www.ncbi.nlm.nih.gov/pubmed/35254403
http://dx.doi.org/10.1084/jem.20211838

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