Case Report: Atypical HUS Presenting With Acute Rhabdomyolysis Highlights the Need for Individualized Eculizumab Dosing

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) is an ultra-rare orphan disease caused by dysregulated complement activation resulting in thrombotic microangiopathy. Although complement-mediated endothelial injury predominantly affects the renal microvasculature, extra-renal manifestations are...

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Detalles Bibliográficos
Autores principales: Benoit, Stefanie W., Fukuda, Tsuyoshi, VandenHeuvel, Katherine, Witte, David, Fuller, Christine, Willis, Jennifer, Dixon, Bradley P., Drake, Keri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906567/
https://www.ncbi.nlm.nih.gov/pubmed/35281224
http://dx.doi.org/10.3389/fped.2022.841051

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