Mapping the gene network landscape of Alzheimer’s disease through integrating genomics and transcriptomics

Integration of multi-omics data with molecular interaction networks enables elucidation of the pathophysiology of Alzheimer’s disease (AD). Using the latest genome-wide association studies (GWAS) including proxy cases and the STRING interactome, we identified an AD network of 142 risk genes and 646...

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Detalles Bibliográficos
Autores principales: Rosenthal, Sara Brin, Wang, Hao, Shi, Da, Liu, Cin, Abagyan, Ruben, McEvoy, Linda K., Chen, Chi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906581/
https://www.ncbi.nlm.nih.gov/pubmed/35213535
http://dx.doi.org/10.1371/journal.pcbi.1009903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906581/
https://www.ncbi.nlm.nih.gov/pubmed/35213535
http://dx.doi.org/10.1371/journal.pcbi.1009903

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