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Mapping the gene network landscape of Alzheimer’s disease through integrating genomics and transcriptomics
Integration of multi-omics data with molecular interaction networks enables elucidation of the pathophysiology of Alzheimer’s disease (AD). Using the latest genome-wide association studies (GWAS) including proxy cases and the STRING interactome, we identified an AD network of 142 risk genes and 646...
Autores principales: | Rosenthal, Sara Brin, Wang, Hao, Shi, Da, Liu, Cin, Abagyan, Ruben, McEvoy, Linda K., Chen, Chi-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906581/ https://www.ncbi.nlm.nih.gov/pubmed/35213535 http://dx.doi.org/10.1371/journal.pcbi.1009903 |
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