Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis

Cholesterol homeostasis is required for the replication of many viruses, including Ebola virus, hepatitis C virus, and human immunodeficiency virus-1. Niemann-Pick C1 (NPC1) is an endosomal-lysosomal membrane protein involved in cholesterol trafficking from late endosomes and lysosomes to the endopl...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortega-Gonzalez, Paula, Taylor, Gwen, Jangra, Rohit K., Tenorio, Raquel, Fernandez de Castro, Isabel, Mainou, Bernardo A., Orchard, Robert C., Wilen, Craig B., Brigleb, Pamela H., Sojati, Jorna, Chandran, Kartik, Sachse, Martin, Risco, Cristina, Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906592/
https://www.ncbi.nlm.nih.gov/pubmed/35263388
http://dx.doi.org/10.1371/journal.ppat.1010322

Ejemplares similares

Ejemplares similares