KLF15 cistromes reveal a hepatocyte pathway governing plasma corticosteroid transport and systemic inflammation

Circulating corticosteroids orchestrate stress adaptation, including inhibition of inflammation. While pathways governing corticosteroid biosynthesis and intracellular signaling are well understood, less is known about mechanisms controlling plasma corticosteroid transport. Here, we show that hepato...

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Detalles Bibliográficos
Autores principales: Jiang, Zhen, Elsarrag, Selma Z., Duan, Qiming, LaGory, Edward L., Wang, Zhe, Alexanian, Michael, McMahon, Sarah, Rulifson, Ingrid C., Winchester, Sarah, Wang, Yi, Vaisse, Christian, Brown, Jonathan D., Quattrocelli, Mattia, Lin, Charles Y., Haldar, Saptarsi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906731/
https://www.ncbi.nlm.nih.gov/pubmed/35263131
http://dx.doi.org/10.1126/sciadv.abj2917

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