Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism

The mediobasal hypothalamus (MBH) is the central region in the physiological response to metabolic stress. The FK506-binding protein 51 (FKBP51) is a major modulator of the stress response and has recently emerged as a scaffolder regulating metabolic and autophagy pathways. However, the detailed pro...

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Detalles Bibliográficos
Autores principales: Häusl, Alexander S., Bajaj, Thomas, Brix, Lea M., Pöhlmann, Max L., Hafner, Kathrin, De Angelis, Meri, Nagler, Joachim, Dethloff, Frederik, Balsevich, Georgia, Schramm, Karl-Werner, Giavalisco, Patrick, Chen, Alon, Schmidt, Mathias V., Gassen, Nils C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906734/
https://www.ncbi.nlm.nih.gov/pubmed/35263141
http://dx.doi.org/10.1126/sciadv.abi4797

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