Coordinated DNA and histone dynamics drive accurate histone H2A.Z exchange

Nucleosomal histone H2A is exchanged for its variant H2A.Z by the SWR1 chromatin remodeler, but the mechanism and timing of histone exchange remain unclear. Here, we quantify DNA and histone dynamics during histone exchange in real time using a three-color single-molecule FRET assay. We show that SW...

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Detalles Bibliográficos
Autores principales: Poyton, Matthew F., Feng, Xinyu A., Ranjan, Anand, Lei, Qin, Wang, Feng, Zarb, Jasmin S., Louder, Robert K., Park, Giho, Jo, Myung Hyun, Ye, Joseph, Liu, Sheng, Ha, Taekjip, Wu, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906749/
https://www.ncbi.nlm.nih.gov/pubmed/35263135
http://dx.doi.org/10.1126/sciadv.abj5509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906749/
https://www.ncbi.nlm.nih.gov/pubmed/35263135
http://dx.doi.org/10.1126/sciadv.abj5509

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