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Coordinated DNA and histone dynamics drive accurate histone H2A.Z exchange
Nucleosomal histone H2A is exchanged for its variant H2A.Z by the SWR1 chromatin remodeler, but the mechanism and timing of histone exchange remain unclear. Here, we quantify DNA and histone dynamics during histone exchange in real time using a three-color single-molecule FRET assay. We show that SW...
Autores principales: | Poyton, Matthew F., Feng, Xinyu A., Ranjan, Anand, Lei, Qin, Wang, Feng, Zarb, Jasmin S., Louder, Robert K., Park, Giho, Jo, Myung Hyun, Ye, Joseph, Liu, Sheng, Ha, Taekjip, Wu, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906749/ https://www.ncbi.nlm.nih.gov/pubmed/35263135 http://dx.doi.org/10.1126/sciadv.abj5509 |
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