Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex

In the neocortex, functionally distinct areas process specific types of information. Area identity is established by morphogens and transcriptional master regulators, but downstream mechanisms driving area-specific neuronal specification remain unclear. Here, we reveal a role for RNA-binding protein...

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Detalles Bibliográficos
Autores principales: Harb, Kawssar, Richter, Melanie, Neelagandan, Nagammal, Magrinelli, Elia, Harfoush, Hend, Kuechler, Katrin, Henis, Melad, Hermanns-Borgmeyer, Irm, Calderon de Anda, Froylan, Duncan, Kent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906809/
https://www.ncbi.nlm.nih.gov/pubmed/35262486
http://dx.doi.org/10.7554/eLife.55199

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