Dynamic Interleukin-1 Receptor Type 1 Signaling Mediates Microglia-Vasculature Interactions Following Repeated Systemic LPS

INTRODUCTION: Lipopolysaccharide (LPS) preconditioning involves repeated, systemic, and sub-threshold doses of LPS, which induces a neuroprotective state within the CNS, thus preventing neuronal death and functional losses. Recently, proinflammatory cytokine, Interleukin-1 (IL-1), and its primary si...

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Detalles Bibliográficos
Autores principales: Nemeth, Daniel P, Liu, Xiaoyu, McKim, Daniel B, DiSabato, Damon J, Oliver, Braedan, Herd, Anu, Katta, Asish, Negray, Christina E, Floyd, James, McGovern, Samantha, Pruden, Paige S, Zhutang, Feiyang, Smirnova, Maria, Godbout, Jonathan P, Sheridan, John, Quan, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906862/
https://www.ncbi.nlm.nih.gov/pubmed/35282272
http://dx.doi.org/10.2147/JIR.S350114

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