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The endoplasmic reticulum proteostasis network profoundly shapes the protein sequence space accessible to HIV envelope

The sequence space accessible to evolving proteins can be enhanced by cellular chaperones that assist biophysically defective clients in navigating complex folding landscapes. It is also possible, at least in theory, for proteostasis mechanisms that promote strict quality control to greatly constrai...

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Detalles Bibliográficos
Autores principales:	Yoon, Jimin, Nekongo, Emmanuel E., Patrick, Jessica E., Hui, Tiffani, Phillips, Angela M., Ponomarenko, Anna I., Hendel, Samuel J., Sebastian, Rebecca M., Zhang, Yu Meng, Butty, Vincent L., Ogbunugafor, C. Brandon, Lin, Yu-Shan, Shoulders, Matthew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906867/ https://www.ncbi.nlm.nih.gov/pubmed/35180219 http://dx.doi.org/10.1371/journal.pbio.3001569

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