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Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment

PURPOSE: In order to overcome the biological barriers at all levels and enhance the delivery efficiency of siRNA, we have prepared a multifunctional siRNA delivery system (CHCE/siRNA nanoparticles) through self-assembly of the carboxymethyl chitosan modified with histidine, cholesterol, and anti-EGF...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangyang, Qin, Bin, Wang, Min, Feng, Junyi, Zhang, Chenglin, Zhu, Chengshen, He, Suqin, Liu, Hao, Wang, Yaohe, Averick, Saadyah E, Vo, Nga T N, Huang, Lei, Liu, Wentao, Wang, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906879/
https://www.ncbi.nlm.nih.gov/pubmed/35280336
http://dx.doi.org/10.2147/IJN.S340926