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Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment
PURPOSE: In order to overcome the biological barriers at all levels and enhance the delivery efficiency of siRNA, we have prepared a multifunctional siRNA delivery system (CHCE/siRNA nanoparticles) through self-assembly of the carboxymethyl chitosan modified with histidine, cholesterol, and anti-EGF...
Autores principales: | Zhang, Xiangyang, Qin, Bin, Wang, Min, Feng, Junyi, Zhang, Chenglin, Zhu, Chengshen, He, Suqin, Liu, Hao, Wang, Yaohe, Averick, Saadyah E, Vo, Nga T N, Huang, Lei, Liu, Wentao, Wang, Zhimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906879/ https://www.ncbi.nlm.nih.gov/pubmed/35280336 http://dx.doi.org/10.2147/IJN.S340926 |
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