Postconditioning with Irisin Attenuates Lung Ischemia/Reperfusion Injury by Suppressing Ferroptosis via Induction of the Nrf2/HO-1 Signal Axis

Iron-dependent lipid peroxidation causes ferroptosis. This study was aimed at verifying that irisin postconditioning can inhibit ferroptosis and minimize lung ischemia/reperfusion (I/R) damage via activating the Nrf2/HO-1 signal axis. We constructed a murine model of I/R lung damage. At the onset of...

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Detalles Bibliográficos
Autores principales: Wang, Yun, Dong, Zhe, Zhang, Zongze, Wang, Yanlin, Yang, Kun, Li, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906956/
https://www.ncbi.nlm.nih.gov/pubmed/35281462
http://dx.doi.org/10.1155/2022/9911167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906956/
https://www.ncbi.nlm.nih.gov/pubmed/35281462
http://dx.doi.org/10.1155/2022/9911167

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