Cargando…
Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody
The effectiveness of SARS-CoV-2 vaccines and therapeutic antibodies have been limited by the continuous emergence of viral variants and by the restricted diffusion of antibodies from circulation into the sites of respiratory virus infection. Here, we report the identification of two highly conserved...
Autores principales: | Li, Cheng, Zhan, Wuqiang, Yang, Zhenlin, Tu, Chao, Hu, Gaowei, Zhang, Xiang, Song, Wenping, Du, Shujuan, Zhu, Yuanfei, Huang, Keke, Kong, Yu, Zhang, Meng, Mao, Qiyu, Gu, Xiaodan, Zhang, Yi, Xie, Youhua, Deng, Qiang, Song, Yuanlin, Chen, Zhenguo, Lu, Lu, Jiang, Shibo, Wu, Yanling, Sun, Lei, Ying, Tianlei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907017/ https://www.ncbi.nlm.nih.gov/pubmed/35344711 http://dx.doi.org/10.1016/j.cell.2022.03.009 |
Ejemplares similares
-
A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants
por: Yang, Zhenlin, et al.
Publicado: (2021) -
Inhalable antibodies for the treatment of COVID-19
por: Yang, Zhenlin, et al.
Publicado: (2022) -
Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer
por: Zhan, Wuqiang, et al.
Publicado: (2022) -
The prominent role of a CDR1 somatic hypermutation for convergent IGHV3-53/3-66 antibodies in binding to SARS-CoV-2
por: Tian, Xiaolong, et al.
Publicado: (2022) -
Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and durable protective immunity against SARS-CoV-2 infection
por: Zang, Jinkai, et al.
Publicado: (2021)