Effect of early granulocyte-colony-stimulating factor administration in the prevention of febrile neutropenia and impact on toxicity and efficacy of anti-CD19 CAR-T in patients with relapsed/refractory B-cell lymphoma

Chimeric Antigen Receptor T cells (CAR-T) are an outbreaking treatment option for relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) are the most common specific toxicities, while severe...

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Detalles Bibliográficos
Autores principales: Liévin, Raphaël, Di Blasi, Roberta, Morin, Florence, Galli, Eugenio, Allain, Vincent, De Jorna, Romain, Vercellino, Laetitia, Parquet, Nathalie, Mebarki, Miryam, Larghero, Jerome, de Kerviler, Eric, Madelaine, Isabelle, Caillat-Zucman, Sophie, Chevret, Sylvie, Thieblemont, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907072/
https://www.ncbi.nlm.nih.gov/pubmed/35094012
http://dx.doi.org/10.1038/s41409-021-01526-0

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