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Computational analysis of the tryptophan cation radical energetics in peroxidase Compound I
Three well-characterized heme peroxidases (cytochrome c peroxidase = CCP, ascorbate peroxidase = APX, and Leishmania major peroxidase = LMP) all have a Trp residue tucked under the heme stacked against the proximal His heme ligand. The reaction of peroxidases with H(2)O(2) to give Compound I results...
Autores principales: | Poulos, Thomas L., Kim, Jenny S., Murarka, Vidhi C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907084/ https://www.ncbi.nlm.nih.gov/pubmed/35064363 http://dx.doi.org/10.1007/s00775-022-01925-8 |
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